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La lentiginosis unilateral parcial es un trastorno pigmentario poco común, caracterizado por la agrupación unilateral de numerosas manchas marrones que . Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal. Partial unilateral lentiginosis colocalized with naevus depigmentosus. S. I. In. Department of Dermatology, Ajou University School of Medicine.

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J Am Acad Parciial. Others suggest that PUL is a frustrated form of type 5 neurofibromatosis [ 12 ]. Open in a separate window. In the year has been indexed in the Medlinedatabase, and has become a vehicle for expressing the most current Spanish medicine and modern.

All have lentigines bilaterally, are autosomal dominant and present multiple abnormalities, in contrast with PUL that presents unilateral distribution without known interaction [ 217 – 20 ].

Partial unilateral lentiginosis, 1,nm Q-switched neodymium-doped yttrium aluminum garnet laser. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

The clinical end point was immediate lightening of pigment or mild erythema without petechiae. Nevus spilus manifests clinically as a grouping of numerous lenticular elements, brownish parcila or papule on a uniform hyperpigmented background, with diameters between 1 and 20 cm subject to appear both in childhood as in adulthood [ 5 ].


Although treatment is not necessary, many patients with facial PUL seek medical help for cosmetic reasons.

Patient photos were taken at baseline Fig. The authors present a case of a rare pigmentation disorderpartial unilateral lentiginosis PULparckal is characterized by multiple lentigines located in only one side of the body with histopathology of lentigine. J Am AcadDermatol 8: Please enter a personalized message to the authors.

J Am AcadDermatol J Clin Cosmet Dermatol. Continuing navigation will be considered as acceptance of this use. No family members have similar lesions. Even though these lesions are reversible after termination of treatment, they could be disfiguring and stressful to the patient. There was no family history of similar pigmented lesions or personal history of neurological problems. It is characterized by small, well delimited, hyperchromic macules, distributed in a limited area of the body, which can affect one or more dermatomes and stop at the median line.

There are reports of Padcial associated to a central nervous system lentiginoeis, such vascular malformation and mental retardation. The researchers disagree regarding the etiology, admitting the possibility of dealing with mosaicism, partial chimerism or a post-zygotic mutation, the same explanation for segmental neurofibromatosis [ 13 – 16 ].

It is of vital importance to carry out an exhaustive clinical historical, that includes a complete physical examination and pertinent complementarity exams to reach a correct diagnosis and the appropriate management and follow-up of the patient. There is a hypothesis that LUP may represent a mosaicism of a generalized form of lentiginosis with melanocytic proliferation likewise the LEOPARD syndromeforming real lentiiginosis simplex and eventually may be subject to malignant transformation [ 2 ].


Lentigo simplex can be induced into the patient by PUVA treatment. Guidelines Upcoming Special Issues. Also, a few cases of PUL were associated with abnormalities of the central nervous system, including mental retardation and ipsilateral cerebrovascular abnormalities with focal epilepsy, leading to the idea that both conditions resulted from a common developmental problem of the neural crest [ 7 ].

Lentiginosis unilateral parcial. | Actas Dermo-Sifiliográficas (English Edition)

We can help you send a request to the authors directly. Go to the members area of the website of the AEDV, https: Sao Paulo, Roca, All articles are subjected to a rigorous process of revision in pairs, and careful editing for literary and scientific style.

Published online Jun 1. This way an alteration in the embryonic development before crest closure could be suggested as a cause, however, there is no alteration in the development [ 12 ]. YAG laser [ 8 ]. Received Apr 5; Accepted May 5. Communications through our website or via email are not encrypted and are not necessarily secure. Pxrcial Partial unilateral lentiginosis PUL lentigonosis an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal skin.

Partial Unilateral Lentiginoses | OMICS International

A low fluence Q-switched Nd: No guarantees or warranties are made regarding any of the information contained herein. Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders. Article in Hautarzt Gerhards G et al.